Hyperlink Problems

[Squeak]

Hi 1st time here so please bear with me.
I have to do a presentation to Notre Dame Uni, about how I work (Teacher).
I have a few online webpages, that I use for my students.
When I acess them from my hard drive, the links do not lead to where they should.
All the links show they are active, and if I cut and paste the links into the URL bar they work fine, but they will not navigate tothe pages when clicked on.
The pages are docs, and webpages, the webpages are made in Dreamweaver, and running on Office XP
Any ideas folks??